Involvement of homocysteine, homocysteine thiolactone, and paraoxonase type 1 ( PON ‐1) in the etiology of defective human sperm function

the investigation of the relationship between type a and type b personalities and quality of translation

چکیده ندارد.

Homocysteine levels, paraoxonase 1 (PON1) activity, and cardiovascular risk.

lyzed our study population by dividing the births within each gestational age category into smaller and larger birth weights by their z score of birth weight by gestational age. Adjusting for gestational week within each category as well as year of birth, larger infants did have the best survival for any given gestational age. For 22 to 27, 28 to 32, 33 to 36, and 37 to 42 weeks, the relative r...

Urinary excretion of homocysteine-thiolactone in humans.

BACKGROUND A metabolite of homocysteine (Hcy), the thioester Hcy-thiolactone, has been implicated in coronary heart disease in humans. Because inadvertent reactions of Hcy-thiolactone with proteins can lead to cell and tissue damage, the ability to detoxify or eliminate Hcy-thiolactone is essential for biological integrity. We examined the hypothesis that the human body eliminates Hcy-thiolacto...

Homocysteine thiolactone affects protein ubiquitination in yeast.

The formation of homocysteine thiolactone (HcyTl) from homocysteine occurs in all examined so far organisms including bacteria, yeast, and humans. Protein N-homocysteinylation at the ε-amino group of lysine is an adverse result of HcyTl accumulation. Since tagging of proteins by ubiquitination before their proteasomal degradation takes place at the same residue, we wondered how N-homocysteinyla...

Mechanism action of homocysteine and its thiolactone in haemostasis system